发明名称 DERIVES DE PROSTAGLANDINES ET MEDICAMENTS CONTENANT CES DERIVES
摘要 A compound of the formula I is prepared by oxidative treatment of a corresponding prostaglandin or prostaglandin-C1 to C4 ester with a halogenating agent. During this process, the 11 hydroxyl and 15 hydroxyl groups can be temporarily protected. By reducing the compounds, in which R denotes bromine or iodine, the corresponding compounds which are unsubstituted in the 5 position can be prepared. The compounds of the formula I, and their reduced derivatives, can be employed as drugs or as intermediates in chemical processes. <IMAGE>
申请公布号 FR2351113(A1) 申请公布日期 1977.12.09
申请号 FR19770014202 申请日期 1977.05.10
申请人 WELLCOME FOUNDATION LTD 发明人 SALVADOR MONCADA, NORMAN WHITTAKER ET HARRY TACON OPENSHAW;WHITTAKER NORMAN;OPENSHAW HARRY TACON
分类号 C07D307/33;A61K31/34;A61K31/341;A61K31/343;A61K31/557;A61P7/02;A61P43/00;C07C405/00;C07D307/935;C07D307/937;(IPC1-7):C07D307/93;A61K31/36;C07C177/00 主分类号 C07D307/33
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