发明名称 TROPENOL DERIVATIVES – INITIAL MATERIAL FOR PRODUCING THERAPEUTICALLY EFFECTIVE COMPOUNDS
摘要 The use of a compound of formula (II) is proposedin which R is a moiety selected from the group C-C-alkyl and C-C-alkylene-phenyl, each optionally can be substituted by hydroxy or C-C-alkoxy, or an acid addition salt or hydrate thereof, optionally in the form of the acid addition salts thereof as well as optionally in the form of the hydrates thereof, as an initial material for producing tropenol having pharmacological properties such as, for example, tiotropium bromide, ipratropium bromide and BEA2108, preferably tiotropium bromide.
申请公布号 EA009808(B1) 申请公布日期 2008.04.28
申请号 EA20050001081 申请日期 2002.06.08
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 发明人 RAPP ARMIN, WALTER;SOBOTTA RAINER
分类号 C07D451/10;C07B61/00;C07D451/02;C07D451/06;C07D471/08;C07D491/18 主分类号 C07D451/10
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