发明名称 |
Polyhydroxyphenylchromanone salts and therapeutic composition |
摘要 |
Salts of polyhydroxyphenylchromanones, e.g., silymarin or one or more members of the silymarin group, are reacted with a monoaminopolyhydroxy alcohol of the formula <IMAGE> wherein X IS AN INTEGER FROM 3 TO 5; AND R1 and R2 are hydrogen, lower alkyl or hydroxyalkyl TO GIVE CHEMOTHERAPEUTIC SALT COMPOUNDS WHICH ARE WATER SOLUBLE WHILE RETAINING A HIGH DEGREE OF MEDICAL EFFECTIVENESS. The salt compounds can be administered to mammals to antagonize or mitigate liver damage and inflammation.
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申请公布号 |
US4061765(A) |
申请公布日期 |
1977.12.06 |
申请号 |
US19760709734 |
申请日期 |
1976.07.29 |
申请人 |
DR. MADAUS & CO. |
发明人 |
MADAUS, ROLF HERMANN HEINRICH;HALBACH, GUNTER;TROST, WILFRIED |
分类号 |
A61K31/335;(IPC1-7):A61K31/33 |
主分类号 |
A61K31/335 |
代理机构 |
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地址 |
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