发明名称 |
BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS |
摘要 |
The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format. |
申请公布号 |
EP2331517(B1) |
申请公布日期 |
2016.06.08 |
申请号 |
EP20090789278 |
申请日期 |
2009.09.09 |
申请人 |
PROMEGA CORPORATION |
发明人 |
KELTS, JESSICA;MEISENHEIMER, PONCHO;SHULTZ, JOHN;CALI, JAMES, J.;MA, DONGPING |
分类号 |
C07D277/68;C07K5/103;C07K5/113;C12Q1/25;C12Q1/26;C12Q1/34;C12Q1/37;C12Q1/48;C12Q1/66;G01N21/76 |
主分类号 |
C07D277/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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