发明名称 |
PROCESS FOR PREPARING OXYME-ETHER COMPOUNDS WITH ANTIDEPRESSIVE ACTIVITY |
摘要 |
The novel compounds of formula I wherein R is hydrogen, methyl or chlorine, R1 is oxygen or sulphur, R2 is OCH2, CH20CH2, OC2H40CH2, R3 is hydrogen or methyl, n and p are 0 or 1 and n + p is 0 or 1 and salts thereof have a very powerful anti-depressive activity which for a considerable part, and in some substances even entirely, is based on serotonine potentiation. Monoamino oxidase inhibition does not contribute to the anti-depressive effect. The substances have a low toxicity and are substantially free from side effects. The compounds can be synthesized and processed to compositions according to known methods. |
申请公布号 |
HU171160(B) |
申请公布日期 |
1977.11.28 |
申请号 |
HU1976PI00515 |
申请日期 |
1976.03.17 |
申请人 |
NV PHILIPS'GLOEILAMPENFABRIEKEN,NL |
发明人 |
WELLE,HENDRICUS B.A.,NL;CLAASSEN,VOLKERT,NL |
分类号 |
A61K31/15;A61K;C07C;C07C67/00;C07C239/00;C07C251/50 |
主分类号 |
A61K31/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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