发明名称 NYA 1-ARYLOXI-2,3-EPOXIPROPANER OCH FORFARANDE FOR DERAS FRAMSTELLNING
摘要 of the disclosure: Compounds of the formula wherein R1 and R1' are the same or different and represent hydrogen, an alkyl or alkoxy radical having 1 - 4 carbon atoms, the allyl radical, halogen or the nitro group and R2 represents an acrylic acid radical or acrylic acid nitrile radical of the formulae or wherein R3 represents hydrogen, a (C1-C5)-alkyl radical, an unsubstituted aryl or aryl lower alkyl radical or an aryl or aryl- lower alkyl radical substituted by lower alkyl or lower alkoxy, R4 represents hydrogen or a (C1-C8)-alkyl radical, and R5 represents hydrogen, a lower alkyl or aryl- lower alkyl radical and process for their manufacture. The compounds according to the invention are valuable intermediate products for the production of 1-aryloxy-2-hydroxy-3-aminopropanes that are used as medicaments for the treatment of heart diseases.
申请公布号 SE7706060(L) 申请公布日期 1977.11.26
申请号 SE19770006060 申请日期 1977.05.24
申请人 HOECHST AG 发明人 STACHE U;FRITSCH W
分类号 A61K31/335;A61K31/336;A61P9/00;C07D303/20;C07D303/22;C07D303/24;C07D303/32;(IPC1-7):C07D303/02 主分类号 A61K31/335
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