发明名称 CHEMOKINE RECEPTOR ANTAGONIST AND METHOD OF USE THEREOF
摘要 PROBLEM TO BE SOLVED: To provide a low molecular weight compound being an antagonist of chemokine receptor function.SOLUTION: The method comprises administering to a subject an effective amount of a compound represented by formulas (I) and (II) or physiologically acceptable salt thereof. (n is an integer from 1 to 4; M is >NR, >CRR, -O-CRR-O-, or -CH-CRR-O-; qis an integer from 0 to 3; qis 0 or 1; Ris H, OH, N, halogen, a substituted/unsubstituted aliphatic group, -SH, CN or the like; and Ris OH, halogen, substituted/unsubstituted alkyl, substituted amino, aliphatic group, aromatic group or the like.)SELECTED DRAWING: None
申请公布号 JP2016138122(A) 申请公布日期 2016.08.04
申请号 JP20160039332 申请日期 2016.03.01
申请人 MILLENNIUM PHARMACEUTICALS INC;KYOWA HAKKO KIRIN CO LTD 发明人 LULY JAY R;NAKASATO YOSHISUKE;OSHIMA ETSUO;HARRIMAN GERALDINE C B;CARSON KENNETH G;GHOSH SHOMIR;ELDER AMY M;MATTIA KAREN M
分类号 C07D401/06;C07D491/044;A61K;A61K31/4353;A61K31/438;A61K31/4427;A61K31/445;A61K31/451;A61K31/4523;A61K31/4525;A61K31/4535;A61K31/4545;A61K31/496;A61K31/506;A61K31/527;A61K31/537;A61K31/5377;A61K31/539;A61K31/55;A61K31/5513;A61P;A61P1/00;A61P1/04;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P11/06;A61P13/12;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P29/00;A61P31/18;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D;C07D211/52;C07D221/00;C07D223/00;C07D223/20;C07D313/00;C07D313/12;C07D337/00;C07D337/12;C07D401/14;C07D405/00;C07D405/06;C07D409/06;C07D451/00;C07D471/04;C07D491/00;C07D491/04;C07D491/052;C07D493/04;C07D495/04;C07D497/04;C07D513/04;C07D519/00 主分类号 C07D401/06
代理机构 代理人
主权项
地址
您可能感兴趣的专利