发明名称 PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS 1-FENIL-PROPIL (2)-PIPERAZINAS RACEMICAS U OPTICAMENTE ACTIVAS.
摘要 <p>1521052 Pharmaceutical compositions BOEHRINGER INGELHEIM GmbH 2 Sept 1975 [3 Sept 1974] 03218/78 Divided out of 1521051 Heading A5B Pharmaceutical compositions in the form of dosage units useful in reducing the blood lipid level and the blood cholesterol level comprise as active ingredient N-[1-(3', 4'- methylenedioxyphenyl) - prop - 2 - yl] - N' - (2- chloro-phenyl)-piperazine or a physiologically compatible acid addition salt thereof in association with a pharmaceutical carrier or excipient, each dosage unit containing greater than 40 mg, but no greater than 60 mg of active ingredient. The compositions may further contain a coronary dilator such as 2, 6- bis-(diethanolamino)-4, 8-dipiperidino pyrimido [5, 4-d] pyrimidine, 3-(#-diethylamino ethyl)- 4-methyl-7-carbethoxymethoxy-2-oxo-2H - chromen, 3, 3'-(N, N'-dimethylethylenediamino)- bis-(propyl 3, 4, 5-trimethoxy benzoate, N-3'- phenylpropyl-(2')-1, 1-diphenyl-(3)-amine,α- isopropyl-α-[N-(methyl-N-homoveratryl)- y - aminopropyl]-3, 4-dimethoxy phenyl-acetonitrile or L-#-(#-hydroxy-α-methyl-phenylethylamino)-3-methoxypropiophenone. The compositions may be administered orally, parenterally or rectally in the form of granules, tablets, coated tablets, capsules, pills, syrups, emulsions, suspensions, powders, drops, suppositories or injection solutions.</p>
申请公布号 ES453934(A1) 申请公布日期 1977.11.16
申请号 ES19340004539 申请日期 1976.12.03
申请人 C. H. BOEHRINGER SOHN 发明人
分类号 C07D317/58;A61K;A61K31/135;A61K31/235;A61K31/24;A61K31/275;A61K31/33;A61K31/35;A61K31/36;A61K31/495;A61K31/505;A61P3/06;A61P7/02;A61P25/00;C07D;C07D241/00;C07D241/04;C07D295/04;C07D295/08;C07D317/50;C07D405/06;C07D405/10;C07D407/06;(IPC1-7):07D/;61K/ 主分类号 C07D317/58
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