发明名称 2-{8 N-(1,3-diamino-isopropyl)-amino{9 -4-phenyl-2-imidazolines and salts thereof
摘要 A compound of the formula <IMAGE> wherein R1 is chlorine, bromine, fluorine or methyl; R2 and R3, which may be identical to or different from each other, are each hydrogen, chlorine or methyl; R4 is hydrogen, methyl or ethyl; and R5 and R6, which may be identical to or different from each other, are each methyl, ethyl or alkoxy-alkyl of 2 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocycle which may contain an additional heteroatom, such as pyrrolidino, piperidino, morpholino, piperazino or hexamethyleneimino; AND NON-TOXIC, PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THE SALTS ARE USEFUL AS ANTITHROMBOTICS.
申请公布号 US4058616(A) 申请公布日期 1977.11.15
申请号 US19760692325 申请日期 1976.06.03
申请人 BOEHRINGER INGELHEIM GMBH 发明人 KUMMER, WERNER;STAHLE, HELMUT;KOPPE, HERBERT;HAARMANN, WALTER;REICHL, RICHARD
分类号 A61K31/415;A61P7/02;C07D233/48;(IPC1-7):A61K31/44;A61K31/41;C07D401/14 主分类号 A61K31/415
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