摘要 |
New antitumor agents designated MA 144-M1 and MA 144-M2, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria, e.g. Staphyococcus aureus, Bacillus subtilis and Sarcina lutea, and inhibit the growth of animal tumors such as leukemia L 1210, P 388 and sarcoma 180 are produced by fermentation of MA 144-producing strains of streptomyces and by the chemical or enzymatic conversion of aclacinomycin A or cinerubin A. |
申请人 |
ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI |
发明人 |
UMEZAWA,HAMAO,PROF.;TAKEUCHI,TOMIO;NAGANAWA,HIROSHI;ISHIZUKA,MASAAKI;SHIBAMOTO,CHIGASAKI;OKI,TOSHIKAZU;INUI,TAIJI |