摘要 |
A process for bonding a ligand to a carrier through the use of a pyrimidine derivative of the formula: <IMAGE> in which R1, R2, R3 and R4 are each independently hydrogen, hydroxyl, halogen, lower alkyl, lower alkoxy, loweralkylthio, loweracylamino, nitro, cyano, carboxamido, loweralkylsulphonyl, loweralkoxycarbonyl, phenyl, trifluoromethyl or chloromethyl, THE LIGAND OR THE CARRIER CONTAINING AT LEAST ONE FUNCTIONAL GROUP THAT REACTS WITH THE PYRIMIDINE DERIVATIVE. |