| 摘要 |
NEW MATERIAL:A compound, expressed by the formula and having following physicochemical properties. Appearance: colorless crystal; Molecular weight: FD-MS m/z 819(M+H)<+>. Elementary analysis (%); C, 66.54; H, 9.29; O, 24.06. Molecular formula; C46H74O12. Melting point; 157.0-159.0 deg.C. Specific rotatory power; [alpha] =-47.0 (C=1.00 methanol). Solubility; soluble in methanol, acetone, ethyl acetate, dimethylsulfoxide, etc., and slightly soluble in water, hexane, etc. Color reaction; positive to phosphorus-molybdic acid reaction, sulfuric acid and potassium permanganate reaction, negative to the Pauly reaction and Rydon- Smith reaction, etc. USE:An antifungal, antitumor agent, vascularization inhibitor or vermicide. PREPARATION:A bacterium strain belonging to the genus Streptomyces such as Streptomyces.bottropensis NK86-0279 (FERM BP-1785) is cultured at 25-30 deg.C for 3-6 days under neutral-slightly acidic conditions. |
