| 摘要 |
Compounds of the formula <IMAGE> wherein R1 denotes optionally substituted phenyl, thienyl, furyl or 1,4-cyclohexadienyl, R2 represents a free carboxyl group or an esterified carboxyl group which can be split physiologically, R3 represents hydrogen, lower alkoxy or an optionally substituted methyl group and B represents an optionally substitued six-membered ring with 1 to 3 ring nitrogen atoms, which is bonded to the carbonyl group -C(=O)- by one of its carbon atoms, the nitrogen atoms of a monocyclic six-membered ring having 2 nitrogen atoms being either adjacent or separated by two ring carbon atoms, and the salts of such compounds which have a salt-forming group, including the inner salts, for example the 7 beta -[D(-)- alpha -(3,5-Dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamido)-phenylace tamido]-cephalosporanic acid, have antibiotic activity. |
