发明名称 METHOD OF OBTAINING 4-AMINO-3,5-DIHALOGENPHENYL-ETHANOLAMINES
摘要 <p>.beta. This invention relates to a new process for the preparation of certain 4-amino-3,5-dihalogeno-phenyl ethanolamines and acid addition salts thereof having valuable physiological properties, in particular an activity on .beta.-receptors. The new process comprises the reduction of the corresponding phenyl-glyoxal or hydrate thereof in the presence of an appropiate amine and the optional subsequent conversion of the compound thus prepared into an acid addition salt thereof. The phenyl-glyoxal derivatives used as starting materials are new compounds and constitute a further feature of the invention. Processes for their preparation are given.</p>
申请公布号 BG23746(A3) 申请公布日期 1977.10.12
申请号 BG19740028068 申请日期 1974.10.29
申请人 DR.KARL*THOMAE GMBH 发明人 KECK,JOHANNES;KRUEGER,GERD;PIERER,HELMUT;NOLL,KLAUS-REINHOLD
分类号 C07C213/00;A61K31/135;A61K31/137;C07C67/00;C07C215/68;(IPC1-7):C07C91/04 主分类号 C07C213/00
代理机构 代理人
主权项
地址