发明名称 |
METHOD OF OBTAINING 4-AMINO-3,5-DIHALOGENPHENYL-ETHANOLAMINES |
摘要 |
<p>.beta. This invention relates to a new process for the preparation of certain 4-amino-3,5-dihalogeno-phenyl ethanolamines and acid addition salts thereof having valuable physiological properties, in particular an activity on .beta.-receptors. The new process comprises the reduction of the corresponding phenyl-glyoxal or hydrate thereof in the presence of an appropiate amine and the optional subsequent conversion of the compound thus prepared into an acid addition salt thereof. The phenyl-glyoxal derivatives used as starting materials are new compounds and constitute a further feature of the invention. Processes for their preparation are given.</p> |
申请公布号 |
BG23746(A3) |
申请公布日期 |
1977.10.12 |
申请号 |
BG19740028068 |
申请日期 |
1974.10.29 |
申请人 |
DR.KARL*THOMAE GMBH |
发明人 |
KECK,JOHANNES;KRUEGER,GERD;PIERER,HELMUT;NOLL,KLAUS-REINHOLD |
分类号 |
C07C213/00;A61K31/135;A61K31/137;C07C67/00;C07C215/68;(IPC1-7):C07C91/04 |
主分类号 |
C07C213/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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