| 摘要 |
1487989 Controlled release liquid compositions TANABE SENAKU CO Ltd 15 Jan 1976 [27 Jan 1975] 01542/76 Heading A5B A controlled release liquid pharmaceutical composition is prepared by a method which comprises the steps of dispersing a phospholipid uniformly in water to give an aqueous phospholipid dispersion in which the liquid spherules have a diameter of less than 5.0u, adding a medicament to the aqueous phospholipid dispersion, freezing the thus-obtained aqueous dispersion thereby trapping the medicament into the lipid spherules, and then thawing the frozen dispersion to give an aqueous suspension of the medicament trapped into lipid spherules having a diameter of less than 5.0Á. |
