摘要 |
<p>Tetralone and indanone compounds of the formula <IMAGE> wherein R1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of 3-6 carbon atoms, F, Cl, Br, NO2, monoalkylamino or dialkylamino, wherein each alkyl is of 1-4 carbon atoms, alkanoyloxy of 1-6 carbon atoms or alkanoylamino of 1-4 carbon atoms; R2 is OH or alkoxy of 1-4 carbon atoms or R1 and R2 collectively are methylenedioxy; R3 is H or CH3; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, F, Cl, Br or CF3; n is 1 or 2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.</p> |