| 摘要 |
<p>1496298 Esters of theophyllinylacetic acid J A WULFING 18 March 1976 [24 March 1975] 10871/76 Heading C2C Novel compounds of the Formula I wherein R is hydrogen or methyl, n is 1 to 4 and Acyl is nicotinoyl, 3-methylpyrazole-5- carbonyl, 3 - methylisoxazolyl - 5 - carbonyl, 5 - n - butylpyridin - 2 - carbonyl, 2 - (4- chlorophenoxy) - 2 - methyl - propionyl, 2- acetoxybenzoyl or theophyllinyl - 7 - acetyl, may be prepared by (a) reacting a compound III with HO-Acyl or an acylating derivative thereof or (b) reacting a compound with theophyllinylacetic acid or an acylating derivative thereof where in both processes X is hydroxyl or a group displaceable on esterification. Pharmaceutical compositions of the compounds I with the usual excipients may be administered orally or parenterally in the treatment of adverse hyperlipedemic states.</p> |
