发明名称 |
Process for the preparation of 6-alkoxy-substituted penicillins |
摘要 |
An improved process of preparing a 6-alkoxy-substituted penicillin or penicillin sulfoxide is disclosed. This process comprises adding a halogenating agent to penicillin or penicillin sulfoxide while cooling, and then adding an alkali metal alcoholate to the hydrogenation product in the presence of an alcohol corresponding to the alcoholate.
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申请公布号 |
US4051126(A) |
申请公布日期 |
1977.09.27 |
申请号 |
US19760704770 |
申请日期 |
1976.07.13 |
申请人 |
YAMANOUCHI PHARMACEUTICAL CO., LTD. |
发明人 |
MURAKAMI, MASUO;ISAKA, ICHIRO;KASHIWAGI, TERUYA |
分类号 |
C07D499/00;C07D499/21;(IPC1-7):C07D499/44;C07D499/58 |
主分类号 |
C07D499/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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