发明名称 |
SUBSTITUTED A-UAMINOOXYCARBOXYLIC ACID HYDRAZIDE DERIVATIVES A ND A PROCESS FOR THE PREPARATION EOF |
摘要 |
<p>Substituted alpha -aminooxycarbohydrazide derivatives of the formula I <IMAGE> are obtained by reacting an alpha -aminooxycarbohydrazide with a compound of the general formula X = O. The substituents have the following meaning: X is a cycloalkylidene radical or a methylene group which is substituted by an alkyl radical with 1-5 carbon atoms and/or phenyl or furyl radical which is optionally substituted by halogen, hydroxyl, nitro and/or amino groups; R is hydrogen or a benzyl radical Y is hydrogen Z is an acyl radical derived from a pyridinecarboxylic acid or Y and Z together are one of the substituents which X can represent. The compounds are valuable tuberculostatics. Compounds substituted on the hydrazide group by isonicotinoyl or 5-nitrofurfurylidene group are particularly effective.</p> |
申请公布号 |
CA1018171(A) |
申请公布日期 |
1977.09.27 |
申请号 |
CA19740214911 |
申请日期 |
1974.11.29 |
申请人 |
RICHTER GEDEON VEGYESZETI GYAR R.T. |
发明人 |
KISFALUDY, LAJOS;DANCSI, LAJOS;PATTHY, AGNES (NEE LUKATS);FEKETE, GYOERGY;SZABO, ISTVAN |
分类号 |
C07D307/52;A61K31/15;A61K31/16;A61K31/341;A61K31/345;A61K31/44;A61K31/4409;A61K31/443;A61K31/455;A61P31/04;A61P31/06;C07C243/34;C07C251/50;C07D211/72;C07D213/86;C07D307/70;C07D307/72;C07D307/73;C07D307/75;C07D405/12 |
主分类号 |
C07D307/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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