| 发明名称 |
FORFARANDE FOR FRAMSTELLNING AV 7-ALKOXI- ELLER 7-ARALKOXI-3-BROMMETYLCEFEMER |
| 摘要 |
7-Alkoxy-3-bromomethyl-3-cephems are provided by reacting a 3-methylenecepham with an alkali metal salt of a lower primary alcohol in the presence of a positive brominating agent at a temperature ranging from about -80 DEG to about 0 DEG C. The 3-bromomethylcephems provided by this invention are useful intermediates for the preparation of known cephalosporin antibiotics. |
| 申请公布号 |
SE7702735(L) |
申请公布日期 |
1977.09.23 |
| 申请号 |
SE19770002735 |
申请日期 |
1977.03.10 |
| 申请人 |
LILLY CO ELI |
发明人 |
KOPPEL G A |
| 分类号 |
A61K;A61K31/54;A61K31/545;A61K31/546;C07C;C07D;C07D501/00;C07D501/04;C07D501/16;C07D501/18;C07D501/20;C07D501/24;C07D501/32;C07D501/34;C07D501/57;C07D501/60;(IPC1-7):C07D501/04 |
主分类号 |
A61K |
| 代理机构 |
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代理人 |
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| 地址 |
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