发明名称 SUBSTITUTED ALKYLPHENONE-O-%AMINOETHYL<OXIMES
摘要 The compounds of the formula <IMAGE> where Hal is Br or Cl and R is ethoxy, methoxymethyl, ethoxymethyl, cyano, methoxyethoxy or cyanomethyl when Hal is Cl and is cyano, methoxy or methoxyethoxy when Hal is Br and their salts have a strong anti-depressive activity resulting in a powerful potentiation of noradrenalin and in a strong serotonin potentiation. Monoamino oxidase inhibition does not provide a basis for the antidepressive activity of these compounds. The compounds are free from noxious side effects to a considerable extent, for example, broncho-constriction and stomach ulceration.
申请公布号 AU1214476(A) 申请公布日期 1977.09.22
申请号 AU19760012144 申请日期 1976.03.18
申请人 PHILIPS@ GLOEILAMPENFABRIEKEN, N.V. 发明人 HENDRICUS BERNARDUS ANTONIUS WELLE;VOLKERT CLAASSEN
分类号 A61K31/15;A61K;A61K31/275;A61P25/24;A61P25/26;C07C;C07C67/00;C07C239/00;C07C249/04;C07C249/12;C07C251/50;C07C251/58;C07D251/64 主分类号 A61K31/15
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