| 发明名称 |
Process for preparing 3-hydroxy cephalosporins |
| 摘要 |
3-Hydroxycephalosporins are prepared by treating a 3-hydroxy-4-bromo-2-(2-formylthio-4-oxo-3-amido or imido-1-azetidinyl)-2-butenoate ester with 1,5-diazabicyclo[3.4.0]non-5-ene (DBN) or 1,5-diazabicyclo[5.4.0]undec-5-ene (DBU) at a temperature of from about 0 DEG C. to about 25 DEG C.
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| 申请公布号 |
US4048162(A) |
申请公布日期 |
1977.09.13 |
| 申请号 |
US19750626683 |
申请日期 |
1975.10.29 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
KUKOLJA, STJEPAN;MURPHY, CHARLES F. |
| 分类号 |
C07D205/095;C07D501/08;C07D501/59;(IPC1-7):C07D501/02 |
主分类号 |
C07D205/095 |
| 代理机构 |
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代理人 |
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| 地址 |
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