发明名称 ANHYDROUS AEROSOL FOAM
摘要 1376649 Aerosol foaming compositions BRISTOL-MYERS CO 7 July 1972 [12 July 1971] 31893/72 Heading C4X [Also in Division A5] An anhydrous aerosol composition which forms a stable but quick-breaking foam comprises (i) a high vapour pressure liquefied propellant, and (ii) a foamable organic liquid and (iii) a solid silicone resin both of which are soluble in the propellant. The composition may also contain a further active ingredient, (iv), e.g. with pharmaceutical, cosmetic or toiletry properties, and additives such as-emollients, lubricants, humectants, abrasives and perfumes. The propellant (i) may be a single compound having a vapour pressure at 70‹ F. of at least 60 p.s.i.g., e.g. CHClF 2 , CClF 2 CF 3 , CCl 2 F 2 , CH 3 CHF 2 , propane or dimethyl ether, or a mixture thereof with less volatile propellants, e.g. CHCl 2 F, C 2 Cl 2 F 4 , CCl 3 F, vinyl chloride, methylene chloride or n- or i-butane, and in general constitutes 2-60% by wt. of the total. The foamable liquid (ii) may constitute 40-95% by wt. of the total and may itself be the active ingredient; specified liquids include hydrocarbon oils, vegetable oils, fatty acids and esters thereof, aliphatic alcohols, polyalkylene glycols, liquid surfactants, mixtures of chlorinated hydrocarbons and mineral oil, methyl salicylate or homomenthyl salicylate, and dimethyl silicones. The solid silicone resin (iii) must be present in sufficient quantity to ensure the production of a stable quick-breaking foam: this will generally be 0À1-10% by wt. of the composition. The resins are well-known materials, typically of average molecular weight 5000-8000, and may be provided in the form of solutions in, e.g. toluene, xylene, dimethyl silicone fluids, mineral oil, hexadecyl alcohol, dioctyl phthalate or sebacate or isopropyl myristate. An active ingredient (iv) if present constitutes 0À1-30% by weight of the total, examples being homomenthyl or methyl salicylate, hexachlorophene, zinc oxide, benzocaine, oil of eucalyptus, camphor, anti-perspirants, antibiotics and enzymes.
申请公布号 PH10854(A) 申请公布日期 1977.09.13
申请号 PH19860000136 申请日期 1972.07.05
申请人 BRISTOL MYERS CO 发明人 MACKLES L
分类号 A61K8/04;A61K8/891;A61K9/12;A61Q1/14;A61Q5/00;A61Q5/02;A61Q15/00;A61Q17/00;A61Q17/04;A61Q19/10;B01F17/54;C09K3/30 主分类号 A61K8/04
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