发明名称 FORFARANDE FOR FRAMSTELLNING AV N-(2-AMINO-3,5-DIBROMBENSYL)-N-METYLCYKLOHEXYLAMIN
摘要 N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine of the formula I <IMAGE> and its acid addition salts are prepared by a novel process in which an ester of 2-amino-3,5-dibromobenzyl alcohol, whose amino group can be protected, is reacted with N-methylcyclohexylamine, any amino protective groups are eliminated, and the product of the process is converted, where appropriate, into an acid addition salt. The compound of the formula I effectively dissolves mucus from the respiratory tract and is used to produce cough-suppressant medicaments.
申请公布号 SE396216(B) 申请公布日期 1977.09.12
申请号 SE19730010071 申请日期 1973.07.18
申请人 DR KARL * THOMAE GMBH 发明人 A * KARJALAINEN
分类号 C07C211/49;A61K31/135;C07C67/00;C07C209/00;C07C209/16;C07C211/53;(IPC1-7):07C87/60;07C87/40 主分类号 C07C211/49
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