发明名称 |
4-(N-SUBSTITUTED AMINO)-2-BUTYNYL-1-CARBAMATES AND THIOCARBAMATES AND DERIVATIVES THEREOF AS CENTRALLY ACTING MUSCARINIC AGENTS |
摘要 |
4-(N-Substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.
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申请公布号 |
CA2022511(A1) |
申请公布日期 |
1991.02.03 |
申请号 |
CA19902022511 |
申请日期 |
1990.08.01 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BERGMEIER, STEPHEN C.;KESTER, JEFFREY A.;MOOS, WALTER H.;TECLE, HAILE;THOMAS, ANTHONY J. |
分类号 |
A61K31/27;A61K31/40;A61K31/495;A61K31/535;A61K31/5375;A61P25/02;A61P25/28;C07C271/20;C07C271/24;C07C271/28;C07C333/04;C07D205/04;C07D211/14;C07D211/22;C07D295/12;C07D295/125;(IPC1-7):C07C271/06;C07C333/02;C07D295/15;A61K31/395 |
主分类号 |
A61K31/27 |
代理机构 |
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代理人 |
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地址 |
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