发明名称 Fabrication of soft contact lens and composition therefor
摘要 A contact lens composition, having improved dimensional stability, suitable for use in the preparation of a corrective hydrated lens or an eye bandage, comprises polymerized random graft copolymers containing (in the dry state) from 67.2% to 79.3% HEMA; from 14.25% to 35% PVP; from 0.1% to 4.04% EDMA; from 0.1% to 2.5% MA; from 0.1% to 5.0% water; from 0 to 4 ppm HQ inhibitor; and from 50 to 250 ppm MEHQ inhibitor. The contact lens composition contains from 45% to 65% water after hydration. An improved method for shaping, polymerizing, and cutting and hydrating the contact lens composition is provided. The polymerization is conducted using only a low temperature initiator, by de-gassing prior to polymerization to remove substantially all oxygen, and by conducting the initial polymerization reaction at from 23 DEG C to 30 DEG C for 16 to 30 hours, during which the heat of the reaction is continuously absorbed to control the reaction exotherm. A closed, rod-shaped casting mold, lined with a polyester film material, is used and the polymeric rod obtained may be cut, machined and polished to obtain the contact lens composition. Thereafter, hydration is conducted in a buffered, 0.85% to 0.9% saline solution, at a pH of 7.0 to 7.1.
申请公布号 US4045547(A) 申请公布日期 1977.08.30
申请号 US19750641466 申请日期 1975.12.17
申请人 WARNER-LAMBERT COMPANY 发明人 LE BOEUF, ALBERT R.;GROVESTEEN, WILLIAM R.
分类号 A61L15/12;A61L15/44;B29D11/00;C08F271/02;G02B1/04;(IPC1-7):A61K9/70 主分类号 A61L15/12
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