摘要 |
Compounds of formula:- (where R = Me or HCO; R1, R2 and R3 = H or acyl of at least 2C, one of R1, R2 and R3 at least must = acyl), can be used for treatment of cardiac insufficiency. Preparation is by reaction of the appropriate bufatrienolide rhamnoside with an acid chloride or anhydride in presence of catalysts such as pyridine and metaboric acid, then purification by column chromatography. |