Modified nickel catalyst systems and their use in reductive alkylation reactions

摘要

N-alkyl substituted amines are produced by reacting amine compounds, nitro compounds or nitroso compounds with an aldehyde or a ketone in the presence of hydrogen and a catalytic amount of a two component or a three component catalyst system, the former comprising a nickel catalyst and an acid, and the latter comprising a nickel catalyst, an acid and sulfur-containing compounds.