| 摘要 |
<p>Benzene derivatives of the formula: <IMAGE> I wherein R1 represents alkyl, R2 represents a group -SR3, -SOR3, -SO2R3, -OR3, -SCONH2, -SCN or -T(CH2)mT1R4 [wherein R3 represeents alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, unsubstituted or substituted aryl, or cycloalkylalkyl, R4 represents hydrogen or alkyl, T and T1 each represent oxygen, sulphur or sulphinyl, and m is an integer from 1 to 7] whose position on the benzene ring is either para to the group -NHCSNHCOOR1 or para to the group -NHCOAZ, A represents a bivalent straight-chain aliphatic hydrocarbon radical of 1 to 4 carbon atoms or a said hydrocarbon radical substituted by at least one methyl group, and Z represents a group of the formula:- <IMAGE> wherein R5 represents hydrogen or alkyl, R6 represents hydrogen, alkyl or phenylalkyl, and R7 represents hydrogen or alkyl, or R6 and R7 together with the nitrogen atom to which they are attached form a 5-,6- or 7-membered heterocyclic ring optionally substituted by alkyl group(s), and X<-> represents a pharmaceutically acceptable anion, are new compounds useful as anthelmintics and antifungal agents.</p> |
