| 摘要 |
<p>New 14, 15-dihydroeburnamenine derivs. are of formula (I) (where R is H, 10- or 11- halogen, 11-amino, 11-formamido or 2-5C 11-alkylamino) (Ie and their acid addn. salts are psychostimulants and increase vigilance. (I) can be used to treat cerebral vascular disorders, cerebral sclerosis, cerebral insufficiency and loss of memory resulting from knocks on the head. (I) are prepd. by hydration in the 14, 15-posn. of the corresp. (3S,16S)eburnamenine in the presence of a noble metal catalyst, e.g. platinum oxide.</p> |
