| 摘要 |
The antibiotic mixture A-7413, which contains the factors A, B, C and D, and the physiologically tolerated salts of factors A, B and C, are obtained by culturing the novel microorganism Actinoplanes sp. NRRL 8122, under submerged, aerobic fermentation conditions, in a culture medium containing assimilable sources of carbohydrate, nitrogen and inorganic salts until a significant quantity of the antibiotic is formed and, where appropriate, forming physiologically tolerated salts of factors A, B and C of the A-7413 antibiotic. The A-7413 antibiotic mixture obtained by the process according to the invention, and the A-7413 compounds obtained by the process, are, for example, useful agents for promoting growth and for controlling dental caries and acne. |
