发明名称 ANALOGUES OF PROSTAGLANDINS
摘要 2,2-Difluoro prostaglandin E, F alpha , F beta , A and B analog are disclosed with intermediates and with processes for making them. These compounds differ from the prostaglandins in that they have two fluoro atoms at the C-2 position in place of the two hydrogen atoms at C-2 in the prostaglandins. These compounds are useful for a variety of pharmacological purposes, including antiulcer, inhibition of platelet aggregation, increase in nasal patency, labor induction at term, and wound healing.
申请公布号 AU1068976(A) 申请公布日期 1977.08.04
申请号 AU19760010689 申请日期 1976.01.30
申请人 UPJOHN CO. 发明人 UDO FRIEDRICH AXEN
分类号 A61K31/23;A61K31/557;A61K31/5575;A61P43/00;C07C51/16;C07C53/19;C07C53/21;C07C67/00;C07C401/00;C07C405/00;C07D307/935;C07D309/12;C07F9/40;C07F9/54 主分类号 A61K31/23
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