摘要 |
<p>The enzyme, penicillin acylase, may be produced in high yield and possess high specific activity from cultures of penicillin acylase-producing microorganisms capable of hydrolytically splitting penicillins to form 6-aminopenicillanic acid (6-APA), and phenylacetic acid, by a purification or enrichment process which includes the steps of contacting a solution containing penicillin acylase and an aluminosilicate whereby the penicillin acylase is sorbed thereon, separating the penicillin acylasealuminosilicate sorbate from said solution and subsequently desorbing penicillin acylase from said aluminosilicate.</p> |