发明名称 |
(1,3)-Diaza-(2)-phospha-cyclohexane derivs. - with pharmacodynamic and germicidal activity, prepd. by reacting phosphordiamide cpds. with malonyl chloride derivs. |
摘要 |
<p>New 1,3-diaza-2-phospha-cyclohexane derivs. are of formula (I) (where R1 is alkyl, cycloalkyl or aryl; and R2, R3 R4 and R5 are H, alkyl, cycloalkyl, alkenyl or aryl). (I) are phosphorous analogues of barbituric acids. Specific cpds. (I) include 1,3-di-n-propyl-2,4,6-trioxo-2-ethoxy 1,3-diaza-2-phospha-cyclohexane. In an example, this is prepd. by reacting malonyl chloride with phosphoric acid ethyl ester bis-n-propyl-amide in Et2O.</p> |
申请公布号 |
DE2600665(A1) |
申请公布日期 |
1977.07.21 |
申请号 |
DE19762600665 |
申请日期 |
1976.01.09 |
申请人 |
ROTH,H.J.,PROF.DR.;LENIG,A.R.;STOCK,W.,DR. |
发明人 |
ROTH,H.J.,PROF.DR.;LENIG,A.R.;STOCK,W.,DR. |
分类号 |
A61K31/675;C07F9/6584;(IPC1-7):07F9/65 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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