| 摘要 |
<p>In the preparation of an o-dialkylaminomethylphenol of the formula <IMAGE> in which R1 and R2 each independently is alkyl with 1 to 6 carbon atoms, or R1 and R2 conjointly with the adjacent nitrogen atom, form a five-membered or six-membered ring, by reacting phenol, formaldehyde or paraformaldehyde and an amine of the formula <IMAGE> the improvement which comprises carrying out the reaction in the presence of an organic liquid which is immiscible with water but which is a solvent for the phenol and amine employed as starting materials and the o-dialkylaminomethylphenol which is formed. Advantageously the amine is dimethylamine or diethylamine, the organic liquid is a member selected from the group consisting of cyclohexane, methylcyclohexane, methylene chloride, chloroform, carbon tetrachloride, ethylene chloride, diethyl ether, dipropyl ether, dibutyl ether, dipentyl ether, methyl butyl ether, ethyl propyl ether, diisopropyl ether and di-isobutyl ether, the reaction is effected at about 10 DEG to 70 DEG C., about 1.1 to 2 moles of phenol, about 1 mole of formaldehyde and about 2.5 to 3.5 moles of the organic liquid, after the reaction the by-product water is separated from the organic liquid containing the o-dialkylaminomethylphenol, the organic liquid is separated from the o-dialkylaminomethylphenol, and the organic liquid is recycled for further reaction.</p> |
