发明名称 FORFARANDE FOR FRAMSTELLNING AV 3-ACYLOXIMETYL-2-CEFEMFORENINGAR
摘要 3-Acyloxymethyl-delta<2>-cephem compounds of the formula (I) <IMAGE> in which the substituents are defined in Claim 1, are obtained by reacting a 3-exomethylenecepham sulphoxide with a mixture of an acyl compound and of an appropriate anhydride at a temperature from 70 to 140 DEG C. The 3-acyloxymethyl-delta<2>-cephem esters of the formula I are generally valuable intermediates in the preparation of cephalosporins with antibiotic activity.
申请公布号 SE7700077(L) 申请公布日期 1977.07.20
申请号 SE19770000077 申请日期 1977.01.04
申请人 LILLY CO ELI 发明人 KOPPEL G A;CHOU T-S
分类号 A61K31/545;A61K31/546;C07D;C07D401/00;C07D501/00;C07D501/04;C07D501/20;C07D501/24;C07D501/26;C07D501/30;C07D501/32;C07D501/34;C07D501/58;C07D501/60;C07D519/00;(IPC1-7):C07D501/04 主分类号 A61K31/545
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