| 摘要 |
<p>3,17-dione used in the synthesis of oestrone, is prepd. by microbiological oxidn. with Fusarium caucasicum of steroids which contain at position 3 a hydroxy or oxo grp., can contain double bondings at positions 4,5,5,6 and/or 16,17, at position 17 an oxo grp. or at position 20 an oxo-substd. side chain is present, and with no other substituents in the steroid skeleton; essentially, continuing oxidation is inhibited by carrying out the fermentation in presence of quinoline or a hydroxyquinoline, pref. 8-hydroxyquinoline.</p> |
