TEMPERATUREMPFINDLICHE, VERMEHRUNGSFAEHIGE, NICHT PATHOGENE VARICELLEN-ZOSTER- VIREN, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE VIREN ENTHALTENDE LEBENDVACCINE

摘要

Non-pathogenic varicella-zoster virus mutants are obtained by induction and isolation of temperature-sensitive mutant strains. N-methyl-N'-nitro-N-nitrosoguanidine is employed as mutagenic agent. The obtained mutants are useful for vaccine production.