| 摘要 |
1479802 Production of 7-amino-3-cephem compounds TAKEDA YAKUHIN KOGYO KK 16 July 1975 [16 July 1974] 29899/75 Heading C2C A cephem compound of the Formula (I) wherein R<SP>2</SP> denotes a nitrogen-containing heterocyclic group, or a salt or ester thereof, is obtained by reacting a compound of the Formula (II) wherein R<SP>1</SP> denotes H, C 1 -C 8 alkylthio group or a nitrogen-containing heterocyclic-thio group, or a salt or ester thereof, with an amino compound of the formula NH 2 R<SP>3</SP>, wherein R<SP>3</SP> denotes OH or an amino group which may be substituted by an alkyl or aryl group, or a salt thereof. The reaction may be conducted in the presence of a solvent, e.g. water, an alcohol, an ether, an alkyl cyanide, a haloform or an alkylene halide, and in the presence of an inorganic or organic acid or using (III) in the form of a salt with an inorganic or organic acid. |
