摘要 |
1,207,094. Arginine; arginine containing peptides. G. D. SEARLE & CO. 21 March, 1969 [26 March, 1968], No. 14874/69. Heading C2C. Arginine and arginine containing peptides are prepared by reacting arginine or the arginine residue in a peptide protected by the group -SO 2 R where R is 1-8C hydrocarbon with HF. Preferred groups are tosyl groups. Ditosyl bradykinin, a compound which possesses a similar pharmacological action to bradykinin, is a preferred peptide starting material and in turn is prepared from its carbobenzyloxy derivative by hydrogenolysis.
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