发明名称 Anti-bacterial benzyl-pyrimidines - esp powerful in combination with sulphonamides
摘要 <p>Benzylpyrimidines of formula (I) and their acid addition salts are new: (where R1 and R2 are alkyl or alkenyl; Z is O linked to one of the N atoms; n = O or 1; A1 is CF3, -C=R6 R7 or -C R8 R9 R10 either (i) R6 is oxo and R7 is H, alkyl or alkoxy, (ii) R6 is NOH and R7 is alkyl or (III) -C=R6 R7 is -CN, R8 and R9 are H or alkyl; R10 is OH, alkoxy or NR3R4; alternatively R9 and R10 are alkoxy or alkylthio, or R9 and R10 is alkylene-dioxy or alkylene-dithio; R3 and R4 are H, alkyl or alkanoyl).</p>
申请公布号 CH589067(A5) 申请公布日期 1977.06.30
申请号 CH19760007423 申请日期 1973.07.27
申请人 HOFFMANN-LA ROCHE, F., & CO. AG 发明人
分类号 C07D239/48;C07D239/49;C07D265/30;(IPC1-7):07D239/48 主分类号 C07D239/48
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