摘要 |
<p>1508338 Pharmaceutical compositions containing organo-silicon compounds SOC CORTIAL 27 Aug 1975 [10 Sept 1974 21 April 1975] 35280/75 Heading A5B [Also in Division C3] Pharmaceutical compositions useful in the treatment of cardiovascular and atherosclerotic diseases having antiatherosclerotic, hypocholesterolaemiatic and hypolipaemiatic activitives, in the form of dosage units comprising at least one organo-silicon compound of formula wherein R represents a hydroxy, alkoxy or an aminocarboxylalkoxy group and M represents a group of the formula -O-C(CH 3 )-, a group of the formula -(CH 2 ) x - (in which x is zero), or except when R represents a hydroxy group, a group of formula -(CH 2 ) x - (in which x is an integer from 1 to 3) or a physiologically acceptable salt thereof, as active ingredient in an amount of from 1 to 1000mg per dosage unit, in association with a pharmaceutical carrier or excipient. The compositions may be in the form of suppositories, capsules and ampoules for oral or parenteral administration.</p> |