Benzenesulfonyl-ureas and process for preparing them

摘要

Benzenesulfonyl-ureas of the formula wherein X represents a) IN WHICH Z represents hydrogen, halogen, a trifluormethyl group, an alkyl or an alkoxyl radical in 4- or 5-position, or Y represents -CH2-CH2-, -CH-(CH3)-CH2-or -CH2-CH-(CH3)-, R represents a radical of A. PENTAMETHYLENE-IMINE, WHICH MAY BE SUBSTITUTED BY 1 TO 3 METHYL GROUP OR BY AN ENDOALKYLENE GROUP OF 1 TO 3 CARBON ATOMS, B. HEXAMETHYLENE-IMINE, WHICH MAY BE SUBSTITUTED BY AN ENDOETHYLENE GROUP IN beta - epsilon -POSITION, C. HEPTAMETHYLENE-IMINE, D. HEXAHYDRO-ISOINDOLINE, TETRAHYDRO-ISOINDOLINE, 4,7-ENDOALKYLENE-HEXAHYDRO-, 4,7-ENDOALKYLENE-TETRAHYDRO-ISOINDOLINE, THE ENDOALKYLENE GROUP OF WHICH MAY CONTAIN 1 - 2 CARBON ATOMS AND THE DOUBLE LINKAGE OF THE TETRAHYDRO GROUP BEING IN 5,6-POSITION, E. N-3-azaspiro-[5,5]-undecane, F. THE GROUPS +TR and their pharmaceutically acceptable alkali- or alkaline earth-metal salts.