发明名称 |
Substituted 2-aminomethyl-6-iodophenols |
摘要 |
Certain substituted 2-aminomethyl-6-iodophenols and their pharmaceutically acceptable acid addition salts wherein the phenyl nucleus may be further substituted with 1 to 3 nuclear substituents are useful as antihypertensive, diuretic and saluretic agents. These products may be prepared by either iodinating a 2-aminomethyl-3,4,5-substituted phenol or hydrolyzing an appropriately substituted N-(2-hydroxy-3-iodo-4,5,6-substituted benzyl)carboxamide under either acidic or basic conditions. |
申请公布号 |
US4029816(A) |
申请公布日期 |
1977.06.14 |
申请号 |
US19760724896 |
申请日期 |
1976.09.20 |
申请人 |
MERCK & CO., INC. |
发明人 |
CRAGOE, JR., EDWARD J.;SCHULTZ, EVERETT M. |
分类号 |
C07C37/14;C07C37/62;C07F3/12;(IPC1-7):A01N9/20;A01N9/24;C07C87/28 |
主分类号 |
C07C37/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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