| 摘要 |
This invention provides a process for the preparation of glycol 2-(p-chlorophenoxy)-2-methylpropionate nicotinate, of formula (I): <IMAGE> (I) which process is characterized in that 2-(p-chlorophenoxy)-2-methylpropionic acid, of formula (II): <IMAGE> (II) is reacted with ethylene oxide in an inert solvent in the presence of a catalyst, to prepare the monoglycol ester of the acid (II), of formula (III): <IMAGE> (III) which is in turn reacted with nicotinic acid chloride in an inert solvent and in the presence of a base, to prepare the final product, of formula (I).
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