| 发明名称 |
BENZYLAMINES |
| 摘要 |
<p>The preparation of novel benzylamines of the formula I <IMAGE> in which the symbols R1 to R5 have the meanings stated in Claim 1, as well as their physiologically tolerated acid addition salts with inorganic or organic acids is described. The compounds of the formula I have valuable pharmacological properties, especially an antiulcer effect, a secretolytic, cough-suppressant effect and an effect enhancing the production of the surfactant or antiatelectasis factor in the alveoli. The compounds of the formula I are prepared by hydrolysing corresponding compounds which, in place of the carboxyl group R3, have a functional derivative of the carboxyl group as substituent.</p> |
| 申请公布号 |
CA1011748(A) |
申请公布日期 |
1977.06.07 |
| 申请号 |
CA19740197507 |
申请日期 |
1974.04.11 |
| 申请人 |
DR. KARL THOMAE GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
KECK, JOHANNES;NOLL, KLAUS-REINHOLD;PIEPER, HELMUT;KRUEGER, GERD;PUESCHMANN, SIGFRID |
| 分类号 |
C07D295/12;A61K31/135;A61K31/16;A61K31/165;A61K31/185;A61K31/19;A61K31/195;A61K31/24;A61K31/275;A61P1/04;A61P11/10;A61P11/14;B01J21/00;B01J23/00;B01J25/00;B01J27/00;B01J31/00;C07B61/00;C07C67/00;C07C209/00;C07C209/08;C07C209/16;C07C209/28;C07C209/36;C07C209/50;C07C209/52;C07C209/62;C07C211/27;C07C211/29;C07C211/49;C07C211/52;C07C211/53;C07C213/00;C07C213/02;C07C215/14;C07C215/28;C07C215/44;C07C215/68;C07C217/82;C07C217/84;C07C225/22;C07C227/00;C07C227/16;C07C227/18;C07C229/54;C07C231/00;C07C231/12;C07C231/14;C07C233/43;C07C233/54;C07C233/80;C07C233/81;C07C237/22;C07C237/30;C07C253/00;C07C255/58;C07C255/60;C07D221/24;C07D295/135;C07D295/155;C07D295/185 |
主分类号 |
C07D295/12 |
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