SYNTHESIS OF NOVEL CEPHALOSPORIN DERIVATIVES

摘要

PURPOSE:Cephalosporin derivatives of formula I [A is mono- or polycylic, Ncontaining, aromatic hetero-ring; R is aryl, thienyl, furyl, cyclohexadienyl, cyclohexenyl; X is -OCOCH3, pyridinium, carbamoyl of formula -OCO-NR1 R2 R1, R2 are 1 - 4C alkyl), -S-Het (hetero-cycle)] and salts thereof; for example, 3-acetoxymethyl-7alpha-methoxy-7parallel-[D-2-(4-hydroxy-1,5-naphthyli dene-3-carbonamido)-2-phenylacetamido] -3-cephem-4-carboxylic acid.