| 摘要 |
Saturated cyclic ketones having 12 to 20 carbon atoms in the ring, such as muscone, are prepared by (a) the reaction of a cyclic olefin with a dihalocarbene, (b) dehalogenation of the resulting dihalobicylic compound to form a cyclic allene, (c) hydration and oxidation of the cyclic allene to form an unsaturated cyclic ketone, and (d) conversion of the unsaturated cyclic ketone to a saturated cyclic ketone, with optional introduction of an alkyl substituent.
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