摘要 |
Cephalosporin C is recovered directly from aqueous media by reacting Cephalosporin C therein with certain alkanoic acid anhydrides, e.g., a haloalkanoic acid anhydride or mixed haloalkanoic-alkanoic acid anhydride, at pH 7 to 11, at 0 DEG to 30 DEG C., treating the acylated mixture with quinoline, lowering the pH, stirring, and separating the N-acylated Cephalosporin C quinoline salt hydrate from the aqueous medium. |