| 摘要 |
1473896 Substituted 8-oxamorphinans BRISTOL-MYERS CO 16 July 1974 [18 July 1973] 31451/74 Heading C2C Novel compounds of formulae wherein R<SP>1</SP> is H, C 1 to C 6 alkyl or C 1 to C 6 alkenyl, wherein R<SP>6</SP> is H or CH 3 ; R<SP>2</SP> is H, C 1 to C 6 alkyl, C 2 to C 6 acyl, cinnamoyl or and R 3 is H or C 1 to C 6 alkyl; and pharmaceutically acceptable acid addition salts thereof are used as analgesics. Formulae XXXX and XXXI include both the dl racemic mixture and the resolved d and l isomers thereof. The preparation of the compounds of the invention is exemplified in the reaction scheme below
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